Rp Met 0.5mg Tablets

tablet is an oral anti-diabetic medicine used to manage type 2 diabetes mellitus. It contains two active ingredients: repaglinide and metformin. Repaglinide is a meglitinide antidiabetic agent, whereas metformin is a biguanide.

This combination works in complementary ways to improve blood sugar control in adults whose diabetes is not adequately controlled with diet, exercise, or single-drug therapy. By helping control blood glucose levels, it reduces the risk of long-term diabetes-related complications when used as advised by a doctor. The most common side effect of tablet is hypoglycemia (low blood glucose).

It is important to recognize the signs of hypoglycemia, which include sweating, dizziness, headache, and shakiness. Other side effects that may occur while taking this medicine include changes in taste, nausea, diarrhea, stomach pain, headache, and upper respiratory tract infections. Some individuals may also experience weight gain while using this medication.

Do not take {{df} if you have type 1 diabetes mellitus, diabetic ketoacidosis (high levels of acid in the blood), or severe kidney or liver disease. Before starting this medication, inform your doctor if you have a history of heart disease, as it may not be suitable for you. Pregnant or breastfeeding women should also consult their doctor before using this medicine.

Dosage

Overdose

Overdose may cause severe hypoglycaemia or lactic acidosis. Immediate medical attention is required. Metformin can be removed by dialysis in severe cases.

Missed a Dose

Skip the missed dose if a meal is skipped. Do not take a double dose to compensate.

Mode of Action

How Does It Work?

Repaglinide stimulates the pancreas to release insulin after meals. Metformin reduces glucose production in the liver and improves insulin sensitivity in the body. Together, they help control both fasting and post-meal blood sugar levels.

Directions for Use

Take this medicine exactly as prescribed by your doctor. Take it before meals, usually within 15 minutes before eating. Skip the dose if you skip a meal. Do not change the dose without medical advice.

Precautions and Warnings

Pregnancy

Can tablet be used during pregnancy?

tablet should be used during pregnancy only if clearly needed. Good blood sugar control is essential during pregnancy, and treatment decisions should be made by a doctor.

Breast Feeding

Can I take tablet while breastfeeding?

This medicine is not recommended during breastfeeding as its components are excreted in milk and may cause low blood sugar in the infant.

Driving

Can I drive after taking tablet?

Hypoglycaemia may affect alertness. Avoid driving if you experience dizziness or low blood sugar symptoms.

Alcohol

Is alcohol safe with tablet?

Excessive alcohol intake should be avoided as it increases the risk of lactic acidosis and hypoglycaemia.

Other General Warnings

Talk to your doctor if

• You have kidney disease or reduced kidney function
• You have liver disease
• You have heart failure or conditions causing low oxygen levels
• You experience dehydration due to vomiting or diarrhoea
• You are elderly, especially above 80 years of age
• You consume alcohol regularly
• You are undergoing surgery or radiological procedures with contrast agents
• You are taking other medicines that affect blood sugar levels

Contraindications

• If you have renal impairment or reduced kidney function
• If you have acute or chronic metabolic acidosis, including diabetic ketoacidosis
• If you are allergic to repaglinide, metformin hydrochloride, or any ingredient of the tablet
• If you have severe hepatic impairment
• If you are taking both gemfibrozil and itraconazole together

Side effects

• Hypoglycaemia
• Diarrhoea
• Nausea
• Vomiting
• Headache
• Upper respiratory tract infection
• Dizziness
• Fatigue
• Abdominal discomfort

Interactions

Interactions with other medicines

• Gemfibrozil
• Itraconazole
• Rifampicin
• Cationic medicines are eliminated by the kidneys
• Other blood glucose-lowering medicines. Inform your doctor about all medicines, supplements, and herbal products you are taking.

Interactions with food items

• Should be taken before meals
• Food reduces the absorption of metformin but does not affect its clinical effectiveness.
• Skipping meals increases the risk of hypoglycaemia.

Storage and disposal

Store below 30°C. Protect from moisture. Keep out of reach of children. Do not use after the expiry date.

Frequently Asked Questions (FAQs)

What type of medicine is tablet?

It is a combination of a meglitinide (repaglinide) and a biguanide (metformin hydrochloride), both of which lower blood glucose through different mechanisms.

How soon does tablet start working?

Repaglinide starts lowering blood glucose shortly after intake, while metformin provides sustained blood sugar control with regular use.

Can I take tablet with other diabetes medicines?

Yes, but only if prescribed by your doctor. Dose adjustment and monitoring may be required.