Eupen S 1.5gm Injection

Eupen S injection is used in hospitals to treat serious infections, such as complicated skin infections, abdominal infections, and meningitis, in children. It is only used when the infection is likely caused by bacteria that this medicine can fight, to prevent antibiotic resistance. Your doctor or nurse will administer this injection, so please do not attempt to use it yourself.

Meropenem works by breaking down the protective walls of bacteria, causing them to die. Sulbactam helps meropenem work better by blocking enzymes made by some bacteria that can destroy antibiotics. While sulbactam doesn’t work on its own, it boosts the overall effect of the treatment when combined.

Do not take this medicine if you are allergic to meropenem, sulbactam, or any similar antibiotics like penicillin. Common side effects include injection site inflammation, nausea, diarrhoea, headache, or skin rash. Let your doctor know if you are pregnant, breastfeeding, or have kidney problems, seizures, or a history of allergic reactions.

Some medications, such as valproic acid and probenecid, can interact with how meropenem or sulbactam works. The medicine should be stored at a temperature below 25°C and kept away from light and heat. Since this injection is given by a healthcare professional, overdoses or missed doses are rare.

Tell your doctor if you feel unwell, have severe diarrhoea, or develop new symptoms during or after treatment.

Dosage

Overdose

Your doctor or nurse will give this medication. Therefore, it is less likely to provide you with more or less of this medicine.

Missed a Dose

You will be monitored by the doctor or nurse as to when Eupen S injection should be given to you. Thus, it is unlikely that a dose of the injection will be missed. If the doctor or nurse might have missed a dose, inform them.

Mode of Action

How Does It Work?

• Meropenem is a powerful antibiotic that kills bacteria responsible for serious infections. It works by preventing the bacteria from building their protective outer wall, which is essential for their survival. Without this wall, the bacteria break apart and die, aiding your body in fighting the infection more effectively.
• Sulbactam is a medication that enhances the effectiveness of certain antibiotics by preventing bacteria from breaking them down. Some bacteria produce special enzymes that can render antibiotics ineffective, thereby reducing the effectiveness of treatment. Sulbactam blocks these enzymes, so the antibiotic can do its job and kill the bacteria. On its own, sulbactam doesn't treat infections, but when combined with other antibiotics, it helps treat tough bacterial infections more effectively.

Directions for Use

• Eupen S injection will be given to you in the hospital by your doctor or nurse. Do not self-inject this medicine.
• Follow any instructions suggested by the doctor or nurse during the procedure or for aftercare.

Precautions and Warnings

Pregnancy

Can I take Eupen S injection during pregnancy?

• It can be prescribed to you by your doctor if necessary, after a careful assessment of the benefits against the risks.
• Consult your doctor if you are pregnant, think you may be pregnant or are planning to have a baby.

Breast Feeding

Can I take Eupen S injection while breastfeeding?

Meropenem has been reported to be excreted in human milk. Caution should be exercised when Eupen S injection is administered to a nursing woman.

Driving

Can I drive if I have taken Eupen S injection?

No known information is available.

Alcohol

Can I consume alcohol with Eupen S injection?

No known information is available.

Other General Warnings

Talk to your doctor if

• You have a history of allergies to penicillin or similar antibiotics, as you may be at risk for a serious allergic reaction.
• You have kidney problems, seizures, epilepsy, or are taking valproic acid, as this medication may increase seizure risk or interact with your current treatment.
• You develop diarrhoea during or after treatment, as it could be a sign of a serious intestinal infection.
• You are pregnant, have issues with sodium or fluid balance, or if your child is receiving this medication, to ensure safe use.
• Your symptoms worsen or new ones appear, as prolonged antibiotic use can lead to the development of resistant or new infections.
• You feel confused, dizzy, or experience tremors or tingling, and avoid driving or using machines until you know how the medicine affects you.

Contraindications

• If you are allergic to meropenem, sulbactam or any other ingredients of Eupen S injection.
• If you have a history of a severe allergic reaction to any other antibiotics, such as penicillins.

Side effects

• Inflammation at the injection site
• Diarrhoea
• Nausea or vomiting
• Headache
• Rash

Interactions

Interactions with other medicines

• Taking probenecid with meropenem can raise the level of meropenem in your blood, so using them together is not recommended.
• If you are taking valproic acid (a seizure medicine), adding meropenem may lower its levels in your blood, which can raise the risk of having seizures. Extra seizure medicine may be needed if meropenem must be used.
• Sulbactam may interact with a group of antibiotics called aminoglycosides (such as tobramycin, amikacin, and gentamicin), especially at high concentrations in laboratory studies. However, this interaction is unlikely to occur in the body at normal doses.
• Taking sulbactam with probenecid can slow the rate at which sulbactam is eliminated from your body.
• Some possible interactions reported with sulbactam may actually be due to the other antibiotic it's combined with, rather than sulbactam itself.

Storage and disposal

• Store this medicine at a temperature of 25 °C or below.
• Protect it from light and heat.
• Keep it out of the reach of children and pets.
• Any unused portion should not be stored and discarded properly.

Frequently Asked Questions (FAQs)

Can this injection be used to treat COVID-19 or viral infections?

No, Eupen S injection only works against bacterial infections. It does not treat viral infections, such as COVID-19, the flu, or the common cold.

Are there any dietary restrictions during treatment?

There are no specific food restrictions; however, staying well-hydrated and eating a balanced diet can aid in recovery. Inform your doctor about any supplements or herbal products you are taking.