BIOCHEM PHARMACEUTICAL INDUSTRIES|MedicinesRx Required

Biotrexate 5mg Injection

Name: Biotrexate 5mg Injection
Brand: BIOCHEM PHARMACEUTICAL INDUSTRIES
Price: 16.79 INR
Availability: InStock

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Overview

Biotrexate Injection has varied used based on conditions such as 'Immunosuppressant action' against psoriasis and rheumatoid arthritis while 'Anti-neoplastic' action against various types of cancer. It contains methotrexate as its active ingredient. It acts by suppressing the immune response, reducing the swelling, stiffness and inflammation along with slowing down the skin proliferation in rheumatoid arthritis and psoriasis respectively, whereas it inhibits or slows down the growth of cancerous cells in various types of cancer.

Biotrexate Injection is given under the medical supervision of a doctor or nurse at the hospital or clinic setup. It should not be consumed orally. It should not be used in pregnant and breastfeeding women.

Inform your doctor about all the medical conditions and medication you have or had.

Usage Instructions

Directions for Use

Biotrexate Injection will be given by a doctor or nurse in a hospital/clinic.
Do not self-inject. Follow any aftercare instructions given by the doctor/nurse.

Safety Information

Precautions and Warnings

Pregnancy

Can Biotrexate Injection be administered during pregnancy?

Biotrexate Injection is not recommended during pregnancy as it can lead to threatened pregnancy along with causing serious harm to the unborn baby. Women of childbearing age should strictly use contraception and avoid pregnancy during its administration period. Inform your doctor if you are pregnant, think you may be pregnant or planning a pregnancy.

Breast Feeding

Can Biotrexate Injection be taken during breastfeeding?

Biotrexate Injection should not be administered during breastfeeding as it can cause harm to the newborn baby. Inform your doctor if you are a nursing mother.

Driving

Can I drive after the administration of Biotrexate Injection?

Do not drive until your vision is clear as the administration of Biotrexate Injection may cause dizziness and drowsiness.

Alcohol

Can I consume alcohol after the administration of Biotrexate Injection?

Alcohol should not be consumed with Biotrexate Injection, as it can increase the side effect. Inform your doctor if you consume it often.

Other General Warnings

Talk to your doctor if

You have liver, kidney or bone marrow disease.
You are pregnant or planning pregnancy and breastfeeding.
You have any known medical condition.
You are on any other medication or therapy.
You have stomach-intestinal or lung disease or conditions such as ulcers, persistent cough.
You have taken any vaccination recently (live vaccine).
You experience any skin reaction or other side effect after taking this medicine.
Biotrexate Injection should not be used in children below 3 years of age.

Dosage

Overdose

The overdose of Biotrexate Injection can cause vomiting, diarrhoea and gastrointestinal bleeding, severe bone marrow suppression, liver toxicity (more likely in patients with pre-existing risk factors for liver disease), sudden shortness of breath and a dry, persistent cough, and fever. A single overdose has also shown a fatal side effect. Another cause of death is bone marrow suppression.
Several deaths have been reported all over the world from methotrexate overdose because of accidentally taking the injection daily instead of once a week dose as prescribed.
This injection will be given by a doctor or nurse. Thus, the chances of overdose are unlikely. However, if you experience any discomfort or specific symptoms, inform your doctor or reach out to the nearest hospital.

Missed a Dose

It is unlikely that the dose of this injection will be missed if you are monitored in a healthcare set up. However, if you have missed taking any dose of this injection, inform your doctor or nurse immediately.

Mode of Action

How Does It Work?

The composition of Biotrexate Injection works by stopping or slowing down the growth of cancer cells and suppressing the immune system. In patients with rheumatoid arthritis, it reduces the activity of the body's immune system. This decreases swelling, pain and stiffness, ultimately improving the function of joints. It also slows down the proliferation of infected skin cells.

FAQs

Frequently Asked Questions (FAQs)

What precautions should I take before treatment with Biotrexate?

The use of the medicine for a prolonged duration may cause liver damage, including cirrhosis (irreversible scarring of the liver), which may be fatal. High doses of this injection can also damage the kidneys and cause their failure. This injection may not be suitable for individuals with psoriasis or rheumatoid arthritis if they: are alcoholics, have alcoholic liver disease or other chronic liver diseases; have an immunodeficiency syndrome; and have a blood deficiency disorder, such as low red blood cell counts, low white blood counts and low blood platelet counts.

Can Biotrexate cause weight gain?

The side effects of Biotrexate Injection are nausea, diarrhoea and an upset stomach, which may cause loss of weight.

Is Biotrexate Injection a steroid?

No, Biotrexate Injection is not a steroid. It is an immunosuppressant and anti-neoplastic medicine.

Can this medicine cause infections?

This medicine is known to affect the immune system that can lead to some serious infections when used inappropriately. Consult your doctor for more details and use strictly as directed.