Azel 40mg Strip Of 28 Tablets

Azel Capsule contains enzalutamide, which is used in the treatment of metastatic castration-resistant prostate cancer (mCRPC) that has progressed on or after docetaxel therapy. It works by blocking the effects of hormones, leading to the death of cancer cells. The doctor determines the dose and duration of this treatment.

Before starting, inform your doctor if you have diabetes, seizures, liver or kidney issues, or if you are taking any medications for infections. Other medicines can affect or be affected by this medication, so inform your doctor about all your medications. This medicine is not recommended during pregnancy or while breastfeeding.

It is vital for both males and females to use effective contraception during treatment to prevent pregnancy. You may be required to undergo regular monitoring of blood glucose levels while receiving treatment.

Dosage

Overdose

Visit a doctor or the nearest hospital immediately, in case of an overdose.

Missed a Dose

In case of a missed dose, take next dose at scheduled time. Do not take more doses than recommended.

Mode of Action

How Does It Work?

Azel Capsule acts by inhibiting the function of androgens (hormones like testosterone). Enzalutamide inhibits the growth and division of prostate cancer cells by inhibiting androgens.

Directions for Use

• Azel Capsule is to be taken orally as directed by the physician
• This capsule can be taken with or without food

Precautions and Warnings

Pregnancy

Can I take Azel Capsule during pregnancy?

Azel Capsule should be strictly avoided during pregnancy.

Breast Feeding

Can I take Azel Capsule while breastfeeding?

Azel Capsule should be strictly avoided during breastfeeding.

Driving

Can I drive if I have consumed Azel Capsule?

Enzalutamide may lead to psychiatric and neurological symptoms like seizures, confusion, lethargy, visual disturbances. Hence caution is advised before driving.

Alcohol

Can I consume alcohol with Azel Capsule?

Interaction of Enzalutamide and alcohol is not known. Consult a doctor before using alcohol with Enzamide.

Other General Warnings

Talk to your doctor if

• You have abnormal kidney, liver and heart function
• You have a clotting disorder
• You have cancer and/or undergoing chemotherapy
• You are taking Warfarin/Anticoagulant therapy

Contraindications

• Known allergy to any ingredients of enzamide capsules
• If you are pregnant or may become pregnant

Side effects

• Fatigue
• Back pain
• Diarrhoea
• Weakness
• Dizziness
• Headache

Interactions

Interactions with other medicines

• CYP2C8 inhibitors like gemfibrozil increases the concentration of Enzalutamide
• CYP3A4 inhibitor itraconazole increases the action of Enzalutamide
• CYP2C8 and strong CYP3A4 inducer rifampin decreases effect of Enzalutamide
• Enzalutamide decreases the synthesis of midazolam, warfarin, and Omeprazole
• Simultaneous use of Enzalutamide with quinidine, disopyramide, amiodarone, sotalol, dofetilide, ibutilide, antiarrhythmic medicinal products, methadone, moxifloxacin, antipsychotics can prolong the QT interval (Abnormal heart rhythm disorder with chaotic heart beats)

Other general Interactions

Patients with heart disease should use Enzalutamide with caution to avoid risk of abnormal heart beats Enzalutamide can increase the risk of developing other types of cancers

Storage and disposal

Store Azel Capsule at room temperature (20-25°C). Store in a dry place. Keep out of reach of children. Protect from light. Do not use the product after expiry date. Do not throw medicine in wastewater or household waste.

Frequently Asked Questions (FAQs)

What contraceptive measures should be taken during Azel Capsule treatment?

Males with female partners should use a condom or any effective contraception during treatment, and for 3 months after the last dose of Enzamide has been taken.

Can I use Azel Capsule along with herbal medicines?

It is best to discuss with your physician about any possible interactions of Enzalutamide and herbal medicines before using both together.