AF 150 Tablet

Af 150 Tablet is an antifungal medicine containing Fluconazole. Af 150 Tablet is used to treat fungal infections caused by various organisms of the skin, blood, urinary tract, mouth, throat and other parts of the body. Fluconazole acts by inhibiting the growth of the fungal cell wall, thus resulting in fungal cell death.

Take this medicine as prescribed by your doctor at a fixed timing to gain optimal benefits. Pregnant and nursing women should not take this medicine. The most common side effects of this medicine are abdominal pain, nausea, vomiting, headache, diarrhoea.

However, these symptoms of side effects are temporary and go away on their own. If these symptoms do not resolve or worsen, consult with your doctor.

Dosage

Overdose

• Symptoms of an overdose of Af 150 Tablet may include feeling or seeing things that are not real (hallucination and paranoid behaviour).
• If you think you have taken too much of this medicine contact your doctor immediately or visit the nearest hospital.

Missed a Dose

If you have missed taking any dose of this medicine, take it as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose of this medicine to compensate for the missed one.

Mode of Action

How Does It Work?

Af 150 Tablet blocks the formation of the cell membrane of the fungus by inhibiting an enzyme. Thus, resulting in fungal cell death.

Directions for Use

Af 150 Tablet should be taken as directed by your doctor. Swallow it as a whole with a glass of water. Take it at a fixed time for optimal results. Do not consume it more than that prescribed by your doctor.

Precautions and Warnings

Pregnancy

Can I take Af 150 Tablet during pregnancy?

• Af 150 Tablet should not be taken during pregnancy as it can cause potential harm to the unborn baby resulting in birth defects at high doses while threatened pregnancy at normal doses. Thus, it should be avoided during pregnancy.
• Inform your doctor if you get pregnant while on this medicine or think you may be pregnant. It is recommended to use contraception at least for one week even after stopping the medicine.

Breast Feeding

Can I take Af 150 Tablet while breastfeeding?

Fluconazole in Af 150 Tablet passes into the breastmilk. Breastfeeding can be continued after a single dose; however, if you are taking this medicine repeatedly or in high doses, breastfeeding is not recommended.

Driving

Can I drive if I have consumed Af 150 Tablet?

You may experience dizziness or fits while taking Af 150 Tablet. If you experience any of these, you should not drive or use any tools or machines while taking this medicine.

Alcohol

Can I consume alcohol with Af 150 Tablet?

Avoid excess alcohol while taking Af 150 Tablet, as alcohol may worsen the side effects like dizziness.

Other General Warnings

Talk to your doctor if

• You have liver disease or kidney diseases.
• You have heart diseases and irregular heart rhythm.
• You have abnormal electrolyte levels (potassium, calcium or magnesium) in your blood.
• You have severe skin reactions.
• You have adrenal insufficiency (a condition where the adrenal gland does not produce sufficient steroid hormone).

Contraindications

• If you are allergic to Fluconazole or any other ingredients of Af 150 Tablet.
• If you are taking medicines like Astemizole, Terfenadine, Cisapride, Pimozide, Quinidine, Erythromycin.

Side effects

• Headache
• Vomiting
• Diarrhoea
• Nausea
• Increased liver enzymes
• Skin rash
• Liver damage (loss of appetite, vomiting, yellowing of your skin)

Interactions

Interactions with other medicines

• Serious interactions - Terfenadine, Voriconazole, Clarithromycin, Erythromycin, Ranolazine, Lomitapide, Donepezil, Pimozide and Quinidine. Never take Fluconazole with these medicines. When used with Fluconazole, these medicines can cause a life-threatening heart rhythm condition (torsades de pointes).
• Medicines used as an anaesthetic like Alfentanil, Fentanyl.
• Medicines used to treat depression like Amitriptyline, Nortriptyline.
• Blood thinners like Warfarin.
• Medicines for anxiety, like Benzodiazepines (Midazolam, Triazolam).
• Medicines to treat fits like Phenytoin, Carbamazepine.
• Medicines for high blood pressure like Nifedipine, Isradipine, Amlodipine, Felodipine and Losartan.
• Medicines used for treating ovarian cancer (Olaparib).
• Medicines used to prevent an organ transplant rejection like Ciclosporin, Everolimus, Sirolimus or Tacrolimus.
• Medicines used for treating cancer (Vincristine, Vinblastine).
• Medicines used for reducing high cholesterol level (Atorvastatin, Simvastatin, and Fluvastatin).
• Medicines for treating pain and inflammation like Celecoxib, Flurbiprofen, Naproxen, Ibuprofen.
• The effect of contraceptive pills might be reduced. The addition of a barrier form of contraception is needed.
• Medicines for HIV (Saquinavir).
• Medicines to control diabetes like Chlorpropamide, Glibenclamide, Glipizide or Tolbutamide.
• Medicines to control asthma (Theophylline).
• Medicines for treating rheumatoid arthritis (Tofacitinib).
• Medicines to treat cystic fibrosis (Ivacaftor).
• Diuretics like Hydrochlorothiazide.
• Medicines used to treat irregular heartbeats (Amiodarone).

Storage and disposal

• Do not store above 25°C.
• Keep it out of the reach of children and pets.

Frequently Asked Questions (FAQs)

What precautions should I take when using Af 150 Tablet?

• Tell your doctor if you are sexually active and discuss effective contraception methods.
• Af 150 Tablet can make your oral contraceptive pills work less efficiently.
• Hence if you are on this medication, then use barrier methods of contraception like condoms.

I have cough, cold, flu, can I take Af 150 Tablet?

No, flu mostly occurs due to viruses. Af 150 Tablet works against fungus and not viruses. Take it only if it is prescribed by your doctor for the complete duration of treatment.

What is Af 150 Tablet used for?

Af 150 Tablet is used to treat fungal infections of the skin, mouth, throat, urinary tract and various other parts of the body such as fingernails and toenails caused by various organisms.